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Galectin-1 Co-clusters CD43/CD45 on Dendritic Cells and Induces Cell Activation and Migration through Syk and Protein Kinase C Signaling

Galectin-1 is a galactoside-binding lectin expressed in multiple tissues that has pleiotropic immunomodulatory functions. We previously showed that galectin-1 activates human monocyte-derived dendritic cells (MDDCs) and triggers a specific genetic program that up-regulates DC migration through the e...

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Main Authors: Fulcher, Jennifer A., Chang, Margaret H., Wang, Shuo, Almazan, Tim, Hashimi, Sara T., Eriksson, Anna U., Wen, Xiangshu, Pang, Mabel, Baum, Linda G., Singh, Ram Raj, Lee, Benhur
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785374/
https://ncbi.nlm.nih.gov/pubmed/19635795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.037507
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