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N- and O-Glycans Modulate Galectin-1 Binding, CD45 Signaling, and T Cell Death
Galectin-1, a β-galactoside-binding protein highly expressed in the thymus, induces apoptosis of specific thymocyte subsets and activated T cells. Galectin-1 binds to N- and O-glycans on several glycoprotein receptors, including CD7, CD43, and CD45. Here we show that galectin-1 signaling through CD4...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2807281/ https://ncbi.nlm.nih.gov/pubmed/19920154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.066191 |
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