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Crystallographic Insight into Collagen Recognition by Discoidin Domain Receptor 2
The discoidin domain receptors, DDR1 and DDR2, are widely expressed receptor tyrosine kinases that are activated by triple-helical collagen. They control important aspects of cell behavior and are dysregulated in several human diseases. The major DDR2-binding site in collagens I–III is a GVMGFO moti...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cell Press
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2807035/ https://ncbi.nlm.nih.gov/pubmed/20004161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.10.012 |
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