TLR4 signaling augments B lymphocyte migration and overcomes the restriction that limits access to germinal center dark zones

B lymphocyte–intrinsic Toll-like receptor (TLR) signals amplify humoral immunity and can exacerbate autoimmune diseases. We identify a new mechanism by which TLR signals may contribute to autoimmunity and chronic inflammation. We show that TLR4 signaling enhances B lymphocyte trafficking into lymph...

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Hlavní autoři: Hwang, Il-Young, Park, Chung, Harrison, Kathleen, Kehrl, John H.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806604/
https://ncbi.nlm.nih.gov/pubmed/19917774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091982
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