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TLR4 signaling augments B lymphocyte migration and overcomes the restriction that limits access to germinal center dark zones
B lymphocyte–intrinsic Toll-like receptor (TLR) signals amplify humoral immunity and can exacerbate autoimmune diseases. We identify a new mechanism by which TLR signals may contribute to autoimmunity and chronic inflammation. We show that TLR4 signaling enhances B lymphocyte trafficking into lymph...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2806604/ https://ncbi.nlm.nih.gov/pubmed/19917774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091982 |
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