A mechanism for the exclusion of low-fidelity human Y-family DNA polymerases from base excision repair

The human Y-family DNA polymerases, Polι, Polη, and Polκ, function in promoting replication through DNA lesions. However, because of their low fidelity, any involvement of these polymerases in DNA synthesis during base excision repair (BER) would be highly mutagenic. Mechanisms, therefore, must exis...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Haracska, Lajos, Prakash, Louise, Prakash, Satya
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 2003
Assuntos:	Research Papers
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280626/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14630940/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1146103
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!