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A mechanism for the exclusion of low-fidelity human Y-family DNA polymerases from base excision repair

The human Y-family DNA polymerases, Polι, Polη, and Polκ, function in promoting replication through DNA lesions. However, because of their low fidelity, any involvement of these polymerases in DNA synthesis during base excision repair (BER) would be highly mutagenic. Mechanisms, therefore, must exis...

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Bibliografske podrobnosti
izdano v:Genes Dev
Principais autores: Haracska, Lajos, Prakash, Louise, Prakash, Satya
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2003
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280626/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14630940/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1146103
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