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A mechanism for the exclusion of low-fidelity human Y-family DNA polymerases from base excision repair

The human Y-family DNA polymerases, Polι, Polη, and Polκ, function in promoting replication through DNA lesions. However, because of their low fidelity, any involvement of these polymerases in DNA synthesis during base excision repair (BER) would be highly mutagenic. Mechanisms, therefore, must exis...

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Publicat a:Genes Dev
Autors principals: Haracska, Lajos, Prakash, Louise, Prakash, Satya
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280626/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14630940/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1146103
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