Crystal structure of a β-catenin/Axin complex suggests a mechanism for the β-catenin destruction complex
The “β-catenin destruction complex” is central to canonical Wnt/β-catenin signaling. The scaffolding protein Axin and the tumor suppressor adenomatous polyposis coli protein (APC) are critical components of this complex, required for rapid β-catenin turnover. We determined the crystal structure of a...
में बचाया:
| में प्रकाशित: | Genes Dev |
|---|---|
| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Cold Spring Harbor Laboratory Press
2003
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280624/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14600025/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1142603 |
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