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Crystal structure of a β-catenin/Axin complex suggests a mechanism for the β-catenin destruction complex
The “β-catenin destruction complex” is central to canonical Wnt/β-catenin signaling. The scaffolding protein Axin and the tumor suppressor adenomatous polyposis coli protein (APC) are critical components of this complex, required for rapid β-catenin turnover. We determined the crystal structure of a...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Cold Spring Harbor Laboratory Press
2003
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC280624/ https://ncbi.nlm.nih.gov/pubmed/14600025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1142603 |
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