Crystal structure of a β-catenin/Axin complex suggests a mechanism for the β-catenin destruction complex

The “β-catenin destruction complex” is central to canonical Wnt/β-catenin signaling. The scaffolding protein Axin and the tumor suppressor adenomatous polyposis coli protein (APC) are critical components of this complex, required for rapid β-catenin turnover. We determined the crystal structure of a...

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Dades bibliogràfiques

Publicat a:	Genes Dev
Autors principals:	Xing, Yi, Clements, Wilson K., Kimelman, David, Xu, Wenqing
Format:	Artigo
Idioma:	Inglês
Publicat:	Cold Spring Harbor Laboratory Press 2003
Matèries:	Research Papers
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280624/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14600025/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1142603
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