Smoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail
The Hedgehog (Hh) family of secreted proteins controls many aspects of growth and patterning in animal development. The seven-transmembrane protein Smoothened (Smo) transduces the Hh signal in both vertebrates and invertebrates; however, the mechanism of its action remains unknown. We found that Smo...
Guardat en:
| Publicat a: | Genes Dev |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280620/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14597665/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1136603 |
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