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Smoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail

The Hedgehog (Hh) family of secreted proteins controls many aspects of growth and patterning in animal development. The seven-transmembrane protein Smoothened (Smo) transduces the Hh signal in both vertebrates and invertebrates; however, the mechanism of its action remains unknown. We found that Smo...

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Detalhes bibliográficos
Publicado no:Genes Dev
Principais autores: Jia, Jianhang, Tong, Chao, Jiang, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280620/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14597665/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1136603
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