Smoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail

The Hedgehog (Hh) family of secreted proteins controls many aspects of growth and patterning in animal development. The seven-transmembrane protein Smoothened (Smo) transduces the Hh signal in both vertebrates and invertebrates; however, the mechanism of its action remains unknown. We found that Smo...

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Veröffentlicht in:	Genes Dev
Hauptverfasser:	Jia, Jianhang, Tong, Chao, Jiang, Jin
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Cold Spring Harbor Laboratory Press 2003
Schlagworte:	Research Papers
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280620/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14597665/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1136603
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