Regulation of Smoothened Trafficking and Abundance in Hedgehog Signaling
The GPCR-family protein Smoothened (Smo) is essential for Hedgehog (Hh) signal transduction in both insects and vertebrates. The regulation of subcellular localization and abundance of Smo is a critical step in Hh signaling. Recent studies have demonstrated that Smo is subjected to ubiquitination me...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2022-03-01
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| Серии: | Frontiers in Cell and Developmental Biology |
| Предметы: | |
| Online-ссылка: | https://www.frontiersin.org/articles/10.3389/fcell.2022.847844/full |
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