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Sildenafil inhibits chronically hypoxic upregulation of canonical transient receptor potential expression in rat pulmonary arterial smooth muscle
In pulmonary arterial smooth muscle cells (PASMCs), Ca(2+) influx through store-operated Ca(2+) channels thought to be composed of canonical transient receptor potential (TRPC) proteins is an important determinant of intracellular free calcium concentration ([Ca(2+)](i)) and pulmonary vascular tone....
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2806156/ https://ncbi.nlm.nih.gov/pubmed/19889962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00629.2008 |
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