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FOXO signaling is required for disuse muscle atrophy and is directly regulated by Hsp70

The purpose of the current study was to determine whether heat shock protein 70 (Hsp70) directly regulates forkhead box O (FOXO) signaling in skeletal muscle. This aim stems from previous work demonstrating that Hsp70 overexpression inhibits disuse-induced FOXO transactivation and prevents muscle fi...

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Hlavní autoři: Senf, Sarah M., Dodd, Stephen L., Judge, Andrew R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806148/
https://ncbi.nlm.nih.gov/pubmed/19864323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00315.2009
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