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FOXO signaling is required for disuse muscle atrophy and is directly regulated by Hsp70
The purpose of the current study was to determine whether heat shock protein 70 (Hsp70) directly regulates forkhead box O (FOXO) signaling in skeletal muscle. This aim stems from previous work demonstrating that Hsp70 overexpression inhibits disuse-induced FOXO transactivation and prevents muscle fi...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2806148/ https://ncbi.nlm.nih.gov/pubmed/19864323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00315.2009 |
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