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Hsp27 inhibits IKKβ-induced NF-κB activity and skeletal muscle atrophy

Heat shock protein 25/27 (Hsp25/27) is a cytoprotective protein that is ubiquitously expressed in most cells, and is up-regulated in response to cellular stress. Previous work, in nonmuscle cells, has shown that Hsp27 inhibits TNF-α-induced NF-κB activation. During skeletal muscle disuse, Hsp25/27 l...

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Detalhes bibliográficos
Main Authors: Dodd, Stephen L., Hain, Brian, Senf, Sarah M., Judge, Andrew R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747674/
https://ncbi.nlm.nih.gov/pubmed/19528257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-124602
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