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The IκB kinases IKKα and IKKβ are necessary and sufficient for skeletal muscle atrophy

Nuclear factor-κB (NF-κB) signaling is necessary for many types of muscle atrophy, yet only some of the required components have been identified. Gene transfer of a dominant negative (d.n.) IKKβ into rat soleus muscles showed complete inhibition of 7-day disuse-induced activation of a κB reporter ge...

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Detalhes bibliográficos
Main Authors: Van Gammeren, Darin, Damrauer, Jeffrey S., Jackman, Robert W., Kandarian, Susan C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630783/
https://ncbi.nlm.nih.gov/pubmed/18827022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-114249
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