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ROS-mediated activation of NF-κB and Foxo during muscle disuse

We examined reactive oxygen species as upstream activators of NF-κB and Foxo in skeletal muscle during disuse atrophy. Catalase, an enzyme that degrades H(2)O(2), was overexpressed in soleus muscles via plasmid injection prior to seven days of hind limb immobilization. The increased catalase activit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dodd, Stephen L., Gagnon, Brittany J., Senf, Sarah M., Hain, Brian A., Judge, Andrew R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796694/
https://ncbi.nlm.nih.gov/pubmed/19813194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.21526
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