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HDAC1 activates FoxO and is both sufficient and required for skeletal muscle atrophy
The Forkhead box O (FoxO) transcription factors are activated, and necessary for the muscle atrophy, in several pathophysiological conditions, including muscle disuse and cancer cachexia. However, the mechanisms that lead to FoxO activation are not well defined. Recent data from our laboratory and o...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Company of Biologists
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3970557/ https://ncbi.nlm.nih.gov/pubmed/24463822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.136390 |
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