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HDAC1 activates FoxO and is both sufficient and required for skeletal muscle atrophy

The Forkhead box O (FoxO) transcription factors are activated, and necessary for the muscle atrophy, in several pathophysiological conditions, including muscle disuse and cancer cachexia. However, the mechanisms that lead to FoxO activation are not well defined. Recent data from our laboratory and o...

詳細記述

保存先:
書誌詳細
主要な著者: Beharry, Adam W., Sandesara, Pooja B., Roberts, Brandon M., Ferreira, Leonardo F., Senf, Sarah M., Judge, Andrew R.
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970557/
https://ncbi.nlm.nih.gov/pubmed/24463822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.136390
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