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HDAC1 activates FoxO and is both sufficient and required for skeletal muscle atrophy

The Forkhead box O (FoxO) transcription factors are activated, and necessary for the muscle atrophy, in several pathophysiological conditions, including muscle disuse and cancer cachexia. However, the mechanisms that lead to FoxO activation are not well defined. Recent data from our laboratory and o...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Beharry, Adam W., Sandesara, Pooja B., Roberts, Brandon M., Ferreira, Leonardo F., Senf, Sarah M., Judge, Andrew R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970557/
https://ncbi.nlm.nih.gov/pubmed/24463822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.136390
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