Rac1 and Rac2 GTPases are necessary for early erythropoietic expansion in the bone marrow but not in the spleen

BACKGROUND: The small Rho GTPases Rac1 and Rac2 have both overlapping and distinct roles in actin organization, cell survival, and proliferation in various hematopoietic cell lineages. The role of these Rac GTPases in erythropoiesis has not yet been fully elucidated. DESIGN AND METHODS: Cre-recombin...

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Autori principali: Kalfa, Theodosia A., Pushkaran, Suvarnamala, Zhang, Xiaoling, Johnson, James F., Pan, Dao, Daria, Deidre, Geiger, Hartmut, Cancelas, Jose A., Williams, David A., Zheng, Yi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2010
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805739/
https://ncbi.nlm.nih.gov/pubmed/20065081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.006239
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