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Rac1 and Rac2 GTPases are necessary for early erythropoietic expansion in the bone marrow but not in the spleen

BACKGROUND: The small Rho GTPases Rac1 and Rac2 have both overlapping and distinct roles in actin organization, cell survival, and proliferation in various hematopoietic cell lineages. The role of these Rac GTPases in erythropoiesis has not yet been fully elucidated. DESIGN AND METHODS: Cre-recombin...

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Detalhes bibliográficos
Main Authors: Kalfa, Theodosia A., Pushkaran, Suvarnamala, Zhang, Xiaoling, Johnson, James F., Pan, Dao, Daria, Deidre, Geiger, Hartmut, Cancelas, Jose A., Williams, David A., Zheng, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805739/
https://ncbi.nlm.nih.gov/pubmed/20065081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.006239
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