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Rac1 and Rac2 GTPases are necessary for early erythropoietic expansion in the bone marrow but not in the spleen

BACKGROUND: The small Rho GTPases Rac1 and Rac2 have both overlapping and distinct roles in actin organization, cell survival, and proliferation in various hematopoietic cell lineages. The role of these Rac GTPases in erythropoiesis has not yet been fully elucidated. DESIGN AND METHODS: Cre-recombin...

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Bibliografiske detaljer
Main Authors: Kalfa, Theodosia A., Pushkaran, Suvarnamala, Zhang, Xiaoling, Johnson, James F., Pan, Dao, Daria, Deidre, Geiger, Hartmut, Cancelas, Jose A., Williams, David A., Zheng, Yi
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805739/
https://ncbi.nlm.nih.gov/pubmed/20065081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.006239
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