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Rac1 and Rac2 GTPases are necessary for early erythropoietic expansion in the bone marrow but not in the spleen

BACKGROUND: The small Rho GTPases Rac1 and Rac2 have both overlapping and distinct roles in actin organization, cell survival, and proliferation in various hematopoietic cell lineages. The role of these Rac GTPases in erythropoiesis has not yet been fully elucidated. DESIGN AND METHODS: Cre-recombin...

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Main Authors: Kalfa, Theodosia A., Pushkaran, Suvarnamala, Zhang, Xiaoling, Johnson, James F., Pan, Dao, Daria, Deidre, Geiger, Hartmut, Cancelas, Jose A., Williams, David A., Zheng, Yi
格式: Artigo
語言:Inglês
出版: Ferrata Storti Foundation 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805739/
https://ncbi.nlm.nih.gov/pubmed/20065081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.006239
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