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Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton

Actin oligomers are a significant structural component of the erythrocyte cytoskeleton. Rac1 and Rac2 GTPases regulate actin structures and have multiple overlapping as well as distinct roles in hematopoietic cells; therefore, we studied their role in red blood cells (RBCs). Conditional gene targeti...

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Detalhes bibliográficos
Main Authors: Kalfa, Theodosia A., Pushkaran, Suvarnamala, Mohandas, Narla, Hartwig, John H., Fowler, Velia M., Johnson, James F., Joiner, Clinton H., Williams, David A., Zheng, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895472/
https://ncbi.nlm.nih.gov/pubmed/16882712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-03-005942
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