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Purification, crystallization and preliminary X-ray analysis of Enterococcus casseliflavus aminoglycoside-2′′-phosphotransferase-IVa

The deactivation of aminoglycoside antibiotics by chemical modification is one of the major sources of bacterial resistance to this family of therapeutic compounds, which includes the clinically relevant drugs streptomycin, kanamycin and gentamicin. The aminoglycoside phosphotransferases (APHs) form...

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書目詳細資料
Main Authors: Toth, Marta, Vakulenko, Sergei, Smith, Clyde A.
格式: Artigo
語言:Inglês
出版: International Union of Crystallography 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805544/
https://ncbi.nlm.nih.gov/pubmed/20057078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109050039
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