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Purification, crystallization and preliminary X-ray analysis of aminoglycoside-2′′-phosphotransferase-Ic [APH(2′′)-Ic] from Enterococcus gallinarum

Bacterial resistance to aminoglycoside antibiotics is primarily the result of deactivation of the drugs. Three families of enzymes are responsible for this activity, with one such family being the aminoglycoside phosphotransferases (APHs). The gene encoding one of these enzymes, aminoglycoside-2′′-p...

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Bibliografiske detaljer
Main Authors: Byrnes, Laura J., Badarau, Adriana, Vakulenko, Sergei B., Smith, Clyde A.
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374173/
https://ncbi.nlm.nih.gov/pubmed/18259066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108001450
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