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Purification and Characterization of Aminoglycoside Phosphotransferase APH(6)-Id, a Streptomycin Inactivating Enzyme

As part of an overall project to characterize the streptomycin phosphotransferase enzyme APH(6)-Id, which confers bacterial resistance to streptomycin, we cloned, expressed, purified and characterized the enzyme. When expressed in E. coli, the recombinant enzyme increased by up to 70-fold the minimu...

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Detalhes bibliográficos
Main Authors: Ashenafi, Meseret, Ammosova, Tatiana, Nekhai, Sergei, Byrnes, W. Malcolm
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942886/
https://ncbi.nlm.nih.gov/pubmed/24248535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-013-1886-1
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