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Purification, crystallization and preliminary X-ray analysis of aminoglycoside-2′′-phosphotransferase-Ic [APH(2′′)-Ic] from Enterococcus gallinarum

Bacterial resistance to aminoglycoside antibiotics is primarily the result of deactivation of the drugs. Three families of enzymes are responsible for this activity, with one such family being the aminoglycoside phosphotransferases (APHs). The gene encoding one of these enzymes, aminoglycoside-2′′-p...

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主要な著者: Byrnes, Laura J., Badarau, Adriana, Vakulenko, Sergei B., Smith, Clyde A.
フォーマット: Artigo
言語:Inglês
出版事項: International Union of Crystallography 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374173/
https://ncbi.nlm.nih.gov/pubmed/18259066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108001450
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