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Purification, crystallization and preliminary X-ray analysis of the aminoglycoside-6′-acetyltransferase AAC(6′)-Im

Bacterial resistance to the aminoglycoside antibiotics is primarily the result of enzymatic deactivation of the drugs. The aminoglycoside N-acetyltransferases (AACs) are a large family of bacterial enzymes that are responsible for coenzyme-A-facilitated acetylation of aminoglycosides. The gene encod...

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Detaylı Bibliyografya
Asıl Yazarlar: Toth, Marta, Vakulenko, Sergei B., Smith, Clyde A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: International Union of Crystallography 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325823/
https://ncbi.nlm.nih.gov/pubmed/22505423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112007117
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