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The Proteostasis Boundary in Misfolding Diseases of Membrane Traffic

Protein function is regulated by the proteostasis network (PN) (Balch et al. (2008) Science, 319:916), an integrated biological system that generates and protects the protein fold. The composition of the PN is regulated by signaling pathways including the unfolded protein response (UPR), the heat sh...

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Autors principals: Hutt, Darren M., Powers, Evan T., Balch, William E.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805282/
https://ncbi.nlm.nih.gov/pubmed/19708088
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