NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells

DNA glycosylases/AP lyases initiate repair of oxidized bases in the genomes of all organisms by excising these lesions and then cleaving the DNA strand at the resulting abasic (AP) sites and generate 3′ phospho α,β-unsaturated aldehyde (3′ PUA) or 3′ phosphate (3′ P) terminus. In Escherichia coli, t...

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Detalhes bibliográficos
Main Authors: Das, Aditi, Wiederhold, Lee, Leppard, John B., Kedar, Padmini, Prasad, Rajendra, Wang, Huxian, Boldogh, Istvan, Karimi-Busheri, Feridoun, Weinfeld, Michael, Tomkinson, Alan E., Wilson, Samuel H., Mitra, Sankar, Hazra, Tapas K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805168/
https://ncbi.nlm.nih.gov/pubmed/16982218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2006.07.003
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