Stimulation of NEIL2-mediated Oxidized Base Excision Repair via YB-1 Interaction during Oxidative Stress

The recently characterized enzyme NEIL2 (Nei-like-2), one of the four oxidized base-specific DNA glycosylases (OGG1, NTH1, NEIL1, and NEIL2) in mammalian cells, has poor base excision activity from duplex DNA. To test the possibility that one or more proteins modulate its activity in vivo, we perfor...

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Main Authors: Das, Soumita, Chattopadhyay, Ranajoy, Bhakat, Kishor K., Boldogh, Istvan, Kohno, Kimitoshi, Prasad, Rajendra, Wilson, Samuel H., Hazra, Tapas K.
Format: Artigo
Jezik:Inglês
Izdano: 2007
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679419/
https://ncbi.nlm.nih.gov/pubmed/17686777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M704672200
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