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Distinct functions of the transcription factors Gata3 and ThPOK during intrathymic CD4 T cell differentiation
The transcription factors Gata3 and Zbtb7b are required for intrathymic CD4 T cell differentiation, but their precise roles in this process remain unclear. Here we show that, contrary to previous findings, Gata3 disruption blocked CD4 T cell lineage differentiation before CD4 lineage commitment, and...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2805063/ https://ncbi.nlm.nih.gov/pubmed/18776904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1647 |
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