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The sequential activation of Gata3 and Thpok is required for the differentiation of CD1d-restricted CD4(+) NKT cells
While most CD4(+) T cells are MHC class II-restricted, a small subset, including CD1d-restricted ‘invariant’ iNKT cells, are selected on non-classical MHC-I or MHC-I-like molecules. We previously showed that the sequential activation of two zinc finger transcription factors, Gata3 and Thpok, promote...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3321374/ https://ncbi.nlm.nih.gov/pubmed/20706986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040534 |
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