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Distinct functions of the transcription factors Gata3 and ThPOK during intrathymic CD4 T cell differentiation

The transcription factors Gata3 and Zbtb7b are required for intrathymic CD4 T cell differentiation, but their precise roles in this process remain unclear. Here we show that, contrary to previous findings, Gata3 disruption blocked CD4 T cell lineage differentiation before CD4 lineage commitment, and...

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Détails bibliographiques
Auteurs principaux: Wang, Lie, Wildt, Kathryn F., Zhu, Jinfang, Zhang, Xianyu, Feigenbaum, Lionel, Tessarollo, Lino, Paul, William E., Fowlkes, B. J., Bosselut, Rémy
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805063/
https://ncbi.nlm.nih.gov/pubmed/18776904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1647
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