Pro-apoptotic activity of bortezomib in gastrointestinal stromal tumor (GIST) cells

Gastrointestinal stromal tumors (GISTs) are caused by activating mutations in the KIT or PDGFRA receptor tyrosine kinase genes. Although more than 85% of GIST patients treated with the small molecule inhibitor imatinib mesylate (Gleevec®) achieve disease stabilization, complete remissions are rare a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Bauer, Sebastian, Parry, Joshua A., Mühlenberg, Thomas, Brown, Matthew F., Seneviratne, Danushka, Chatterjee, Payel, Chin, Anna, Rubin, Brian P., Kuan, Shih-Fan, Fletcher, Jonathan A., Duensing, Stefan, Duensing, Anette
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805033/
https://ncbi.nlm.nih.gov/pubmed/20028860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1449
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados