Pro-apoptotic activity of bortezomib in gastrointestinal stromal tumor (GIST) cells

Gastrointestinal stromal tumors (GISTs) are caused by activating mutations in the KIT or PDGFRA receptor tyrosine kinase genes. Although more than 85% of GIST patients treated with the small molecule inhibitor imatinib mesylate (Gleevec®) achieve disease stabilization, complete remissions are rare a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bauer, Sebastian, Parry, Joshua A., Mühlenberg, Thomas, Brown, Matthew F., Seneviratne, Danushka, Chatterjee, Payel, Chin, Anna, Rubin, Brian P., Kuan, Shih-Fan, Fletcher, Jonathan A., Duensing, Stefan, Duensing, Anette
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805033/
https://ncbi.nlm.nih.gov/pubmed/20028860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1449
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