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The DREAM complex in anti-tumor activity of imatinib mesylate in gastrointestinal stromal tumors (GISTs)

PURPOSE OF REVIEW: Although most gastrointestinal stromal tumors (GISTs) respond well to treatment with the small molecule kinase inhibitor imatinib mesylate (Gleevec), the majority of patients achieve disease stabilization and complete remissions are rare. Furthermore, discontinuation of treatment...

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Detalhes bibliográficos
Publicado no:Curr Opin Oncol
Main Authors: DeCaprio, James A., Duensing, Anette
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236229/
https://ncbi.nlm.nih.gov/pubmed/24840522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCO.0000000000000090
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