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The DREAM complex in anti-tumor activity of imatinib mesylate in gastrointestinal stromal tumors (GISTs)

PURPOSE OF REVIEW: Although most gastrointestinal stromal tumors (GISTs) respond well to treatment with the small molecule kinase inhibitor imatinib mesylate (Gleevec), the majority of patients achieve disease stabilization and complete remissions are rare. Furthermore, discontinuation of treatment...

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Bibliographic Details
Published in:Curr Opin Oncol
Main Authors: DeCaprio, James A., Duensing, Anette
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4236229/
https://ncbi.nlm.nih.gov/pubmed/24840522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCO.0000000000000090
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