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BINDING AND ACTIVATION OF DNA TOPOISOMERASE III BY THE RMI1 SUBUNIT

Rmi1 is a conserved OB-fold protein that is associated with RecQ DNA helicase complexes from humans (BLM-TOP3α) and yeast (Sgs1-Top3). Although human Rmi1 stimulates the dissolution activity of BLM-TOP3α, its biochemical function is unknown. Here we examined the role of Rmi1 in the yeast complex. Co...

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Detalhes bibliográficos
Main Authors: Chen, Chi-Fu, Brill, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804875/
https://ncbi.nlm.nih.gov/pubmed/17693398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M705427200
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