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Mapping the DNA Topoisomerase III Binding Domain of the Sgs1 DNA Helicase

Several members of the RecQ family of DNA helicases are known to interact with DNA topoisomerase III. Here we show that the S. cerevisiae Sgs1 and Top3 proteins physically interact in cell extracts and bind directly in vitro. Sgs1 and Top3 proteins co-immunoprecipitate from cell extracts under strin...

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Main Authors: Fricke, William M., Kaliraman, Vivek, Brill, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado: 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818744/
https://ncbi.nlm.nih.gov/pubmed/11124263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M009719200
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