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Mapping the DNA Topoisomerase III Binding Domain of the Sgs1 DNA Helicase

Several members of the RecQ family of DNA helicases are known to interact with DNA topoisomerase III. Here we show that the S. cerevisiae Sgs1 and Top3 proteins physically interact in cell extracts and bind directly in vitro. Sgs1 and Top3 proteins co-immunoprecipitate from cell extracts under strin...

詳細記述

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書誌詳細
主要な著者: Fricke, William M., Kaliraman, Vivek, Brill, Steven J.
フォーマット: Artigo
言語:Inglês
出版事項: 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818744/
https://ncbi.nlm.nih.gov/pubmed/11124263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M009719200
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