The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics

Crystallographic analysis revealed that the 17-member polyketide antibiotic lankacidin produced by Streptomyces rochei binds at the peptidyl transferase center of the eubacterial large ribosomal subunit. Biochemical and functional studies verified this finding and showed interference with peptide bo...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Auerbach, Tamar, Mermershtain, Inbal, Davidovich, Chen, Bashan, Anat, Belousoff, Matthew, Wekselman, Itai, Zimmerman, Ella, Xiong, Liqun, Klepacki, Dorota, Arakawa, Kenji, Kinashi, Haruyasu, Mankin, Alexander S., Yonath, Ada
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804743/
https://ncbi.nlm.nih.gov/pubmed/20080686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914100107
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker