Keratin 18 attenuates estrogen receptor α-mediated signaling by sequestering LRP16 in cytoplasm

BACKGROUND: Oncogenesis in breast cancer is often associated with excess estrogen receptor α(ERα) activation and overexpression of its coactivators. LRP16 is both an ERα target gene and an ERα coactivator, and plays a crucial role in ERα activation and proliferation of MCF-7 breast cancer cells. How...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Meng, Yuanguang, Wu, Zhiqiang, Yin, Xiaoyun, Zhao, Yali, Chen, Meixia, Si, Yiling, Yang, Jie, Fu, Xiaobing, Han, Weidong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2009
Aiheet:
Research article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804594/
https://ncbi.nlm.nih.gov/pubmed/20035625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-10-96
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia