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Id2 promotes the invasive growth of MCF-7 and SKOV-3 cells by a novel mechanism independent of dimerization to basic helix-loop-helix factors

BACKGROUND: Inhibitor of differentiation 2 (Id2) is a critical factor for cell proliferation and differentiation in normal vertebrate development. Most of the biological function of Id2 has been ascribed to its helix-loop-helix motif. Overexpression of Id2 is frequently observed in various human tum...

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Main Authors: Meng, Yuanguang, Gu, Chenglei, Wu, Zhiqiang, Zhao, Yali, Si, Yiling, Fu, Xiaobing, Han, Weidong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654660/
https://ncbi.nlm.nih.gov/pubmed/19257909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-75
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