An LRP16-containing preassembly complex contributes to NF-κB activation induced by DNA double-strand breaks

The activation of NF-κB has emerged as an important mechanism for the modulation of the response to DNA double-strand breaks (DSBs). The concomitant SUMOylation and phosphorylation of IKKγ by PIASy and ATM, respectively, is a key event in this mechanism. However, the mechanism through which mammalia...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Wu, Zhiqiang, Wang, Chunmeng, Bai, Miaomiao, Li, Xiaolei, Mei, Qian, Li, Xiang, Wang, Yao, Fu, Xiaobing, Luo, Guangbin, Han, Weidong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Genome Integrity, Repair and Replication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381070/
https://ncbi.nlm.nih.gov/pubmed/25735744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv161
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