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Keratin 18 attenuates estrogen receptor α-mediated signaling by sequestering LRP16 in cytoplasm

<p>Abstract</p> <p>Background</p> <p>Oncogenesis in breast cancer is often associated with excess estrogen receptor α(ERα) activation and overexpression of its coactivators. LRP16 is both an ERα target gene and an ERα coactivator, and plays a crucial role in ERα activat...

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Bibliografiske detaljer
Main Authors: Si Yiling, Chen Meixia, Zhao Yali, Yin Xiaoyun, Wu Zhiqiang, Meng Yuanguang, Yang Jie, Fu Xiaobing, Han Weidong
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2009-12-01
Serier:BMC Cell Biology
Online adgang:http://www.biomedcentral.com/1471-2121/10/96
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