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Nucleotide Excision Repair of a DNA Interstrand Cross-Link Produces Single and Double Strand Breaks
The DNA radical resulting from formal hydrogen atom abstraction from the thymidine methyl group, 5-(2′-deoxyuridinyl)methyl radical, forms interstrand cross-links with the opposing 2′-deoxyadenosine. This is the first chemically characterized, radical mediated cross-link between two opposing nucleot...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2804059/ https://ncbi.nlm.nih.gov/pubmed/20000382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901603h |
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