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Double Strand Break Formation During Nucleotide Excision Repair of a DNA Interstrand Cross-link

The DNA interstrand cross-link (ICL) resulting from the C4′-oxidized abasic site (C4-AP) is a unique clustered lesion comprised of a cross-link adjacent to a nick. The ICL is a substrate for the UvrABC nucleotide excision repair system. The strand containing the nick is preferentially incised, but t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sczepanski, Jonathan T., Jacobs, Aaron C., Van Houten, Bennett, Greenberg, Marc M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725361/
https://ncbi.nlm.nih.gov/pubmed/19606890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901006b
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