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Double Strand Break Formation During Nucleotide Excision Repair of a DNA Interstrand Cross-link
The DNA interstrand cross-link (ICL) resulting from the C4′-oxidized abasic site (C4-AP) is a unique clustered lesion comprised of a cross-link adjacent to a nick. The ICL is a substrate for the UvrABC nucleotide excision repair system. The strand containing the nick is preferentially incised, but t...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2725361/ https://ncbi.nlm.nih.gov/pubmed/19606890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901006b |
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